The October issue examines the technologies that are slowly, but surely, disrupting the healthcare sector. In this extraordinary time in healthcare, technology has the ability to change everything. Artificial Intelligence and Big Data automates and expedites the identification of patients at risk of disease and the recommended treatment courses of action. The Internet of Medical Things, comprised of some 500,000 medical devices, increases the speed and accuracy of diagnosis and treatment of disease and allows doctors to monitor patients’ status in real time. Blockchain technology will securely store medical records, ensuring accurate information for all participants on the chain, including healthcare workers, insurers, patients and pharmacists. Big Tech companies—including Alphabet, Amazon, Apple and Microsoft—are elbowing their way into the healthcare space, providing cloud storage and analytics, e-commerce distribution of medical supplies and pharmaceuticals, and patient healthcare hubs via smart phone. Ultimately, new technologies—including augmented reality, virtual reality, 3D printing, genomic information and gene editing—will transform today’s healthcare system into a responsive efficient system that improves our quality of life and longevity.